Enjoying and learning every day in protein research in Zaragoza

We are a group of postdocs and PhD students working on biotechnology and biomedicine research projects involving proteins.

We gather diverse academic trainings, which make us quite a versatile group. While our expertises change from time to time, we often combine web lab experiments with biocomputation to solve specific problems using a variety of techniques. We work both in individual projects and in collaborative projects involving several members of the group and/or external collaborators worldwide.

Zaragoza provides a pleasant atmosphere to visitors and residents alike and has many things to discover and very friendly people to enjoy them with. Most of the time, our group enjoys an international composition which enriches us greatly.

Know the Team


Carlos Gustavo Genzor

Protein engineering applied to the study of electron transfer reactions in redox proteins.

Certest Biotech

Juan Fernández-Recio

Apoflavodoxin folding and molecular interactions in proteins: energetic and mutational analysis.


Ana Isabel Gracia

Modulation of the redox potential of electron transport proteins by amino acids of the active site.


Susana Maldonado

Study of the initial stages of protein folding with complementary protein fragments.

María Pilar Irún

Structure of the thermal intermediate and the unfolding transition state of apoflavodoxin. Energetics of charged and neutral hydrogen bridges.

Claudia Machicado

Towards the generation of ligand-bearing proteins: molecular modeling of protein-ligand complexes and automatic screening of ligand libraries.

UPCH (Peru)

Luis Alberto Campos

Energetic and structural analysis of a model protein with a three-state equilibrium: flavodoxin from Anabaena PCC 7119.


Jon López

Propellers, loops and fused globules. Structural and energetic study on apoflavodoxin from Anabaena PCC 7119.

CPIAR (Peru)

Marta Bueno

Stability and stabilization of proteins with the Anabaena PCC 7119 apoflavodoxin model.

University of Pittsburgh, (EE.UU.)

Idolka Pedroso

Conformational Stability of an Anti Hepatitis C Antibody and a Derived ScFv Mini Antibody.

Consejo de Seguridad Nuclear

Nunilo Cremades

Helicobacter pylori flavodoxin: conformational landscape and identification of specific inhibitors.


Xabier Arias

Low-density lipoprotein receptor modulus 5: mechanistic implications of its stability, folding, and molecular interactions.

Antelope Dx, (Belgium)

Sara Ayuso

Structural and thermodynamic analysis of the conformations that populate the thermal denaturation of apoflavodoxin from Anabaena PCC 7119.


Vladimir Espinosa

A bioinformatics study of the conformational flexibility and misfolding of proteins.

CardiOmix S.r.l (Italy) & CCB (Singapore)

Juan Martínez Oliván

Mechanism of cellular incorporation of LDL and β-VLDL: structural and functional analysis of the extracellular region of the LDL receptor.

Certest Biotech

Jorge Estrada Collado

Computational tools for the study of protein stability and the interaction between proteins and small molecules.

Alayans Media

Juan José Galano Frutos

Helicobacter pylori: Biomolecular events associated with the appearance of resistance and the anion / water exchange mechanism on the surface of Fld. Optimization design of new compounds with pharmacological activities.


Emilio Lamazares

Rational stabilization of apoflavodoxin from Anabaena PCC 7119 and study of the relevance of its thermal intermediate.

Universidad de Concepción (Chile)

Ángela Rodríguez

Biochemical and structural characterization of flavodoxin from Streptococcus pneumoniae strain TIGR4.

UCC (Colombia)

Alejandro Mahía

New therapeutic and analytical tools based on organic molecules with the ability to interact with proteins implicated in Alzheimer's disease, Parkinson's disease, phenylketonuria and the infection caused by Helicobacter pylori.

Aarhus University (Denmark)

María Conde Giménez

Pharmacological chaperones in phenylketonuria: study of the PAH enzyme unfolding and identification of compounds with pharmacological properties.

Certest Biotech

Sandra Salillas

Combating resistance associated with Helicobacter pylori: synthesis and in vivo evaluation of new antimicrobials against specific bacterial targets.